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Regimens to Get You Started on Feminizing Hormone Therapy

Transitioning, or feminizing hormone therapy, is a process of developing more feminine secondary sex characteristics through the use of hormones. These drugs ease the production of male sex hormones like testosterone and dihydrotestosterone (DHT) while increasing the production of estrogen and progesterone. Benefits of transitioning include a drop in the risk of developing prostate cancer, an increase in bone density, and reduction in body hair. However, these benefits come with side effects that may be slightly challenging to deal with at first. Thankfully, there are 10 regimens to get you started on transitioning.

What is feminizing hormone therapy

Feminizing hormone therapy, also called hormone replacement therapy, or HRT, is the process of administering estrogen and, or progesterone to reduce the production of testosterone in the body. Estrogen, a female sex hormone, can be taken orally, topically, or injected directly into a muscle to promote breast growth and increase body fat. It can also be used to help with the reduction of facial and body hair, redistribution of body fat, increased libido, and mood stabilization. Progesterone, another hormone produced in women’s ovaries, can be taken orally and helps with the reduction of acne, reduction of body hair, increase in breast size, and reduction in sex drive.

Pros of transitioning:

  • Reduces the risk of prostate cancer: Men with low testosterone levels are at higher risk for developing prostate cancer. As the amount of estrogen rises during feminizing HRT, it lowers DHT production, which is linked to the cancer.
  • Increased bone density: As estrogen and progesterone rise with HRT, the amount of testosterone in the body decreases. This drop in T is linked to increased bone density, which can help prevent bone fractures as your transition progresses.
  • Decrease in body hair: Body hair decreases with estrogen and progesterone treatments because these hormones inhibit the 5-ar enzyme that promotes hair growth.

Cons of transitioning:

  • Mood swings: In the first few months of transitioning, there is a slight risk of experiencing mood swings, but these usually subside by the second or third month. If you notice that your mood has been severely affected after one or two months of estrogen therapy, talk to your doctor.
  • Weight gain: HRT may cause weight gain, but this is usually due to an increase in estrogen, especially in people who are overweight. Those who are at a healthy weight before HRT generally do not experience weight gain.
  • Increased libido: High levels of estrogen can stimulate and increase sexual desire. This can be a nuisance if you prefer a lower libido.
  • Increased risk for breast and uterine cancer: The risk for breast cancer rises with the amount of estrogen in your body. Therefore, breast exams and mammograms are advised every six months. The risk of uterine cancer also increases if you take estrogens orally.

Tips for coping with the side effects of transitioning

  • Get an annual prostate exam: Since prostate cancer is more common in older men, it is advised to get an annual prostate exam, even after transitioning.
  • Wear sunscreen daily: Excessive exposure to UV rays can increase the risk of skin cancer and wrinkles.
  • Get annual mammograms: After transitioning, it is highly advised to get an annual breast exam, even if you are a cisgender man because breast cancer occurs in both men and women.
  • Wear sunglasses: Sunglasses can protect the eyes from UV rays. Transitioning does not protect against wrinkles and the breakdown of collagen in the skin.
  • Eat healthy and exercise regularly: HRT is usually combined with a healthy diet and regular exercise to promote a healthy body.

2-month HRT regimen

This regimen lasts two months, as most hormone therapies do. It is ideal for those who are transitioning from testosterone therapy. For this regimen, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection.

2.5-month HRT regimen

This is a two-and-a-half-month transition regimen. It is a great option for those who have been taking testosterone therapy for a while and want to transition sooner. For this regimen, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection.

3-month HRT regimen

This transition regimen lasts three months. For this transition regimen, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection.

4-month HRT regimen

This is a four-month transition regimen. For this transition regimen, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection. In the fourth week, you should take your full daily dose of estrogen.

5-month HRT regimen

This is a five-month transition regimen. For this transition regimen, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection. In the fourth week, you should take your full daily dose of estrogen. In the fifth week, you should take a lower dose of estrogen, in addition to the progesterone injection.

6-month HRO regimens: 6MO/6MO, 7MO/7MO

These regimens are 6-month and 7-month hormone replacement therapies. For these transitional regimens, you should take estradiol orally every day. You should also take an injection of progesterone once every two weeks. In the first week, you should take an estradiol dose that is half your daily dose, in addition to the progesterone injection. In the second week, you should take your daily dose of estradiol, in addition to the progesterone injection. In the third week, you should take another lower dose of estrogen and the progesterone injection. In the fourth week, you should take your full daily dose of estrogen. In the fifth week, you should take a lower dose of estrogen, in addition to the progesterone injection. In the sixth week, you should take another lower dose of estrogen, in addition to the progesterone injection. In the seventh week, you should take your full daily dose of estrogen.

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