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Kombiglyze XR

Kombiglyze XR is a prescription medicine that contains two diabetes medicines, metformin and saxagliptin.


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Kombiglyze XR – Metformin + Saxagliptin – 1000mg + 5mg

  • Brand: Riax MXR
  • Manufacturer:
  • Disease: Diabetes Type 2

Kombiglyze XR is used to improve blood sugar (glucose) control in adults with type 2 diabetes mellitus who do not have adequate blood sugar control with diet and exercise alone.

Kombiglyze XR should not be used in people who are allergic to any of its ingredients or those with: severe kidney problems; or a condition called lactic acidosis, which is an uncommon but serious problem that can happen when you have too much lactic acid in your blood. Lactic acidosis can cause death. Tell your doctor if you have ever had liver problems, including hepatitis C. Your doctor will need to check you for these conditions before prescribing Kombiglyze XR.

It is important to know the symptoms of low blood sugar (hypoglycemia). These symptoms may include: shakiness; dizziness; sweating; confusion; headache; blurred vision;; hunger; fast heart rate and anxiety. If you experience any of these symptoms, eat or drink something containing carbohydrates right away.

Saxagliptin works by blocking the action of DPP-4 enzymes which normally break down incretin hormones such as GLP-1 and GIP after meals Saxagliptin does not work when taken alone and must be taken together with metformin

Frequently asked Questions

What is Kombiglyze XR used for?

Kombiglyze XR is used to improve blood sugar control in adults with type 2 diabetes mellitus. It is not known if Kombiglyze XR is safe and effective in children under 18 years of age. Kombiglyze XR may cause serious side effects, including: lactic acidosis (a build-up of lactic acid in the blood), which can cause death; severe allergic reactions; and problems with your liver or pancreas. You should not take Kombiglyze XR if you have severe kidney problems, are on dialysis, or have conditions that could cause lactic acidosis such as heart failure, recent heart attack, or stroke.

Before starting Kombiglyze XR, tell your doctor if you have ever had: a heart attack; chest pain (angina); congestive heart failure; liver disease; pancreatitis (inflammation of the pancreas); kidney disease; or an allergy to saxagliptin or metformin hydrochloride extended-release tablets. Tell your doctor about all the medicines you take including prescription and over-the-counter medicines, vitamins, and herbal supplements because they may interact with Kombatglyce XLX. Especially tell your doctor if you take: digoxin (Lanoxin ® ); water pills (diuretics) such as hydrochlorothiazide (HCTZ, HydroDIURIL ®, others); phenytoin sodium capsules USP(Dilantin ® ) ; warfarin sodium tablets USP(Coumadin ® ) ; rifampicin capsules USP( Rifadin ®, Rimactane ® ); St John’s wort Do not drink alcohol while taking this medicine because it can increase some of the side effects.

Kombatglyce XLX contains two medications used to treat type 2 diabetes – Saxagliptin and Metformine HCl ER tablet. The combination pill helps improve blood sugar levels when taken together properly under a doctors care. Some people who take this medication may experience adverse effects such as Lactic Acidosis which is a build up of Lactic Acid in their bloodstream that can lead to death. Patients also need to be aware of potential interactions between other drugs they are taking prescribed by their physician along with Konmb

How does Kombiglyze XR work?

Kombiglyze XR is used to improve blood sugar control in adults with type 2 diabetes mellitus. Kombiglyze XR should not be used in people with type 1 diabetes or diabetic ketoacidosis. Kombiglyze XR may cause lactic acidosis, a serious condition that can lead to death. Lactic acidosis occurs when there is too much lactic acid in the blood and it can happen even if you have never had lactic acidosis before. Get emergency medical help right away if you have any of the following symptoms: unusual tiredness, severe drowsiness, fast or slow heartbeat, trouble breathing, stomach pain with nausea and vomiting, cold or blue hands and feet, feeling lightheaded or dizzy; because these may be signs of lactic acidosis.

Metformin controls blood sugar by decreasing the amount of glucose made by your liver and helping your body use insulin better. Saxagliptin helps control blood sugar by increasing levels of insulin after meals.. When taken together as part of Kombogylize XR these two medications work together to help improve blood sugar control for adults with type 2 diabetes mellitus.

Komboglyze has been shown to provide significant reductions from baseline HbA1c at 26 weeks across all doses studied (2.5 mg/500 mg; 5 mg/500 mg; 10 mg/1000mg) – including placebo – versus dual therapy including sulfonylurea (-0.9%, -1%, -1%), thiazolidinedione (-0.8%,-1,-1%) monotherapy (-0.,7% vs metformin monotherapy).

Who manufactures Kombiglyze XR?

Kombiglyze XR is used to treat type 2 diabetes in adults. Kombiglyze XR may be used alone, with other diabetes medicines, or with insulin.

Metformin is a biguanide medicine that helps control blood sugar levels in people with type 2 diabetes by decreasing the amount of sugar made by the liver and increasing the body’s sensitivity to insulin. Saxagliptin is an oral dipeptidyl peptidase-4 (DPP-4) inhibitor which works by increasing levels of incretins in your body. Incretins are hormones that help control blood sugar levels after meals by slowing down the rate at which food leaves your stomach and helping your pancreas release more insulin to move glucose from your blood into cells where it can be used for energy. When taken together, these two medicines help improve blood sugar control while reducing risk of low blood sugar when taken as directed.*

The most common side effects of Kombiglyze XR include headache, nausea, diarrhea, vomiting and abdominal pain.* Like all medications though individual results may vary so always speak to you healthcare provider if you have any questions or concerns about taking this medication

What is the price for Kombiglyze XR?

The medicine contains two ingredients: metformin and saxagliptin. Metformin helps to control blood sugar levels, while saxagliptin helps the body to produce more insulin. Kombiglyze XR is taken once a day, with or without food.

Kombiglyze XR may cause some side effects, including nausea, vomiting, diarrhea, and constipation. However, most people tolerate the medication well. It is important to speak with your doctor if you experience any adverse effects while taking Kombiglyze XR.

If you are struggling with type 2 diabetes, talk to your doctor about whether Kombiglyze XR may be right for you. This medication can help control blood sugar levels and improve overall health outcomes in people with diabetes.

Is there a generic for Kombiglyze XR?

It contains the medications metformin and saxagliptin, which work together to help control blood sugar levels. Metformin helps the body use insulin more effectively, while saxagliptin helps to slow the production of sugar in the liver. Kombiglyze XR comes in tablet form and is taken once daily with food.

Kombiglyze XR can be an effective treatment for type 2 diabetes when used as prescribed. In clinical studies, it was shown to improve blood sugar control as well as A1C levels (a measure of long-term blood sugar control). Additionally, Kombiglyze XR was found to be safe and well tolerated by patients.

If you are taking Kombiglyze XR or any other medications for type 2 diabetes, it is important to follow your doctor’s instructions carefully and monitor your blood sugar levels regularly. Contact your doctor if you have any questions or concerns about your medication regimen or how best to manage your diabetes.

Specification: Kombiglyze XR


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