Diane 35 is an injectable drug that has been approved for the treatment of adult women with primary hyperlipidemia, or high cholesterol. It’s also sometimes used off-label to reduce the appearance of cellulite. But what you might not know is that it can also be used as a part of transgender hormone therapy. Whether you identify as a man, woman, or somewhere in between, Diane 35 can be beneficial for reducing your body fat and increasing your lean muscle mass — which is important if you’re working on losing weight through hormone therapy. In this post, we’ll take a look at exactly what Diane 35 is and how it can help with hormone replacement therapy in transgender people.
What is Diane 35?
Diane 35 is a brand name for the drug drospirenone-ethinylestradiol, which is a combined oral contraceptive pill (or “the pill”). The pill is generally prescribed to women who want to prevent pregnancy, but it can also be used to treat acne, excessive hair growth, and can be helpful in reducing the appearance of cellulite. In fact, Diane 35 is the most widely prescribed brand of the combined oral contraceptive pill in the world. It’s been around for more than 40 years and has been used by an estimated 100 million women in countries including the United States, Canada, the United Kingdom, France, Germany, Australia, and New Zealand.
How does it work?
Diane 35 works by increasing the level of certain sex hormones in the body, including estrogen and progesterone. As we age, our hormone levels drop and cause a number of changes in our bodies, such as decreased muscle mass, increased body fat, decreased bone mineral density, and an increased risk of various diseases like heart disease, diabetes, Alzheimer’s, and osteoporosis. With the help of hormone therapy, you can replace these naturally occurring sex hormones and reverse these negative changes. The combined oral contraceptive pill — like Diane 35 — is a synthetic form of estrogen, which is meant to replace the amount of estrogen your body normally produces (which decreases as you age). The progesterone in Diane 35 helps regulate the amount of estrogen in your body, which helps prevent negative changes associated with low estrogen.
Tips for Using Diane 35 During Hormone Therapy
- Find the right dose for you
- The amount of estrogen in a single dose of Diane 35 can vary from 20 mcg to 80 mcg, which is why it’s important to work with your doctor to determine the correct dose for you.
- Use it the right way
- The pill is taken orally and can be used daily, weekly, or even monthly, depending on your specific needs
- Take it at the same time every day Because the pill is an oral contraceptive, it’s recommended that you take it at the same time every day to help regulate your hormone levels
- Choose the right time of the month to take it
- Because Diane 35 is a combination pill, it should be taken at the same time each day for 21 days followed by 7 days off
When can you use it in hormone therapy?
Because the pill has estrogen in it, you should only use Diane 35 if you are not experiencing any of the following conditions:
- You have a history of blood clots (deep vein thrombosis).
- You have a high risk of developing blood clots.
- You have severe liver disease.
- You’re breastfeeding. If you are experiencing any of these conditions, you may want to use a different form of hormone therapy.
In these cases, a non-estrogen hormone therapy or an anti-androgen hormone therapy may be more appropriate.
Is it safe for transgender people?
Yes, Diane 35 is a safe and effective form of hormone therapy for transgender people. As we mentioned above, Diane 35 contains synthetic estrogen and progesterone, which can help to reduce your body fat and increase your muscle mass. It can also prevent you from developing osteoporosis and can help with hot flashes and night sweats associated with menopause. In addition to estrogen and progesterone, Diane 35 also contains 35 micrograms of drospirenone, which is an oral progestin. This synthetic version of progestin can help reduce your risk of developing certain types of cancers, including endometrial and ovarian cancer.
Final words: Should You Use Diane 35 for Transgender Hormone Therapy?
Diane 35 is a safe and effective form of hormone therapy for both men and women, and especially beneficial for people who are working on losing weight through hormone therapy. If you are experiencing menopause symptoms or want to reduce your risk of developing certain types of cancers, you may want to talk to your doctor about using Diane 35 as a part of your hormone therapy. If you’re thinking about using Diane 35 as part of your hormone therapy, it’s important to remember that it’s not the only option available. You can also use other forms of estrogen and progestin, such as estradiol, estradiol valerate, or norethindrone, along with estradiol.
Source: MtF transition